Molekula Lopinavir
Specification & product details.
Lopinavir is a protease inhibitor used in the treatment of HIV infection. It is available as a research chemical with a molecular formula of C37H48N4O5, a…
CAS number: 192725-17-0
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Specifications
| Property | Value |
| Appearance | White to off white powder |
| Specific rotation | -22° to -26° |
| Heavy metals | ≤ 20 ppm |
| Identification | Conforms to reference (IR,HPLC) |
| Sulphated Ash | ≤ 0.2% |
| Assay (HPLC) | 98% -102% |
| Residue on Ignition | <0.2% |
| Water (KF) | ≤ 4.0% |
| Version | To report |
Storage & handling
| Property | Value |
| Storage Temperature | 2 to 8 °C |
| Acidity | Neutral |
Literature values
Published physical properties of the substance, not batch specifications.
| Property | Value |
| Appearance | White to light tan powder |
| Melting Point | 124-127 °C |
| Water Solubility | Practically insoluble in water |
| Solubility (other solvents) | Freely soluble in methanol and ethanol; soluble in isopropanol |
Identification
| Property | Value |
| SKU | 89983914 |
| CAS Number | 192725-17-0 |
| IUPAC Name | (2S)-N-\[(2S,4S,5S)-5-\[\[2-(2,6-dimethylphenoxy)acetyl\]amino\]-4-hydroxy-1,6-diphenylhexan-2-yl\]-3-methyl-2-(2-oxo-1,3-diazinan-1-yl)butanamide |
| Molecular Formula | C37H48N4O5 |
| Molecular Weight | 628.80 |
| Exact Mass | 628.3625 |
| SMILES | CC1=C(C(=CC=C1)C)OCC(=O)N\[C@@H\](CC2=CC=CC=C2)\[C@H\](C\[C@H\](CC3=CC=CC=C3)NC(=O)\[C@H\](C(C)C)N4CCCNC4=O)O |
| InChIKey | KJHKTHWMRKYKJE-SUGCFTRWSA-N |
| InChI | InChI=1S/C37H48N4O5/c1-25(2)34(41-20-12-19-38-37(41)45)36(44)39-30(21-28-15-7-5-8-16-28)23-32(42)31(22-29-17-9-6-10-18-29)40-33(43)24-46-35-26(3)13-11-14-27(35)4/h5-11,13-18,25,30-32,34,42H,12,19-24H2,1-4H3,(H,38,45)(H,39,44)(H,40,43)/t30-,31-,32-,34-/m0/s1 |
| PubChem CID | 92727 |
| REACH Code | Y110 |
| HTS Code | 29335995 |
| Tariff Code | 2933599590 |
Safety & GHS
Warning
- Health HazardGHS07
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H373May cause damage to organs through prolonged or repeated exposure
Precautionary statements
- P261Avoid breathing dust/fume/gas/mist/vapours/spray
- P280Wear protective gloves/protective clothing/eye protection/face protection
- P302+352IF ON SKIN: Wash with soap and water
- P304+340IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing
- P305+351+338IF IN EYES: Rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing
- P308+313IF exposed or concerned: Get medical advice/attention
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Alternative names
A 157378; A 157378.0; ABT 378; ABT-378/r; Aluviran; Koletra; Lopinavir RS; Lopinavir, (s-(2s,4s,5s))-; Lopinavirum; LPV
Product documentation
Product specification PDF. Batch-specific certificates of analysis and safety data sheets are available on request.
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